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3018870
Dermatomyositis Autoantibody Panel
DERM PAN2
Ordering Recommendation
May be useful for evaluation of patients with characteristic cutaneous manifestations of dermatomyositis with or without muscle weakness.
New York DOH Approval Status
This test is New York state approved.
Specimen Required
Patient Preparation
Collect
Serum separator tube (SST)
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transfer one 1 mL serum aliquots to ARUP standard transport tubes. (Min: 0.5 mL/aliquot)
Storage/Transport Temperature
Refrigerated
Unacceptable Conditions
Hemolyzed, hyperlipemic, icteric, heat-treated, or contaminated specimens
Remarks
Stability
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Methodology
Qualitative Immunoprecipitation / Qualitative Immunoblot / Semi-Quantitative Indirect Fluorescent Antibody (IFA)
Performed
Sun-Sat
Reported
7-18 days
Reference Interval
| Test Number |
Components |
Reference Interval |
|---|---|---|
| TIF-1 gamma (155 kDa) Ab | Negative | |
| NXP2 (Nuclear matrix protein-2) Ab | Negative | |
| MDA5 (CADM-140) Ab | Negative | |
| SAE1 (SUMO activating enzyme) Ab | Negative | |
| Antinuclear Antibody (ANA), HEp-2, IgG | Less than 1:80 | |
| P155/140 Antibody | Negative | |
| Mi-2 (nuclear helicase protein) Antibody | Negative |
Interpretive Data
Refer to report.
Compliance Category
Laboratory Developed Test (LDT)
Note
Antibodies: Mi-2, P155/140, SAE1, MDA5, NXP2, TIF1-gamma, ANA
Hotline History
N/A
CPT Codes
83516 x2; 84182 x4; 86039
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2010852 | Mi-2 (nuclear helicase protein) Antibody | 18485-3 |
| 2010855 | P155/140 Antibody | 8061-4 |
| 2013996 | Dermatomyositis Interpretive Information | 48767-8 |
| 3000090 | Antinuclear Antibody (ANA), HEp-2, IgG | 21424-7 |
| 3000096 | ANA Interpretive Comment | 49311-4 |
| 3001786 | SAE1 (SUMO activating enzyme) Ab | 82440-9 |
| 3001787 | MDA5 (CADM-140) Ab | 82424-3 |
| 3001788 | NXP2 (Nuclear matrix protein-2) Ab | 82426-8 |
| 3001789 | TIF-1 gamma (155 kDa) Ab | 82448-2 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Dermatomyositis Autoantibody Panel
