ADAMTS13 Antibody

3000182
copy
 

Copy Utility


emailprint
Example Reports
High
Normal
Ordering Recommendation

Assist in distinguishing between inherited and acquired forms of thrombotic thrombocytopenic purpura (TTP).  Not recommended as initial test for identification of autoantibodies to ADAMTS13, since the ADAMTS13 antibody test is less specific for acquired TTP than ADAMTS13 Inhibitor (3000228).  Order when acquired TTP is suspected but antibodies are not identified by the ADAMTS13 inhibitor test.  

Mnemonic
ADAMTS AB
Methodology

Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Tue

Reported

1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Draw specimen prior to plasma exchange therapy.

Collect

Light Blue (Sodium Citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation

Transfer 1 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Serum or EDTA plasma. Clotted or hemolyzed specimens.

Remarks
Stability

Ambient: 2 hours; Refrigerated: Unacceptable; Frozen: 2 weeks (No freeze/thaw cycles.)

Reference Interval

Negative: Less than 12 U/mL
Borderline: 12-15 U/mL
Positive: Greater than 15 U/mL

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

83520

Are you an ARUP Client? Click here for your pricing.
Components
Component Test Code* Component Chart Name LOINC
3000192 ADAMTS13 Antibody 34590-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • VWF Cleaving Protease Antibody
ADAMTS13 Antibody