Coccidioides Antibodies, IgM and IgG by Immunoassay, CSF
Ordering Recommendation
Use to screen for the presence of coccidioidal IgM and IgG antibodies in CSF. Not recommended as a standalone test. For comprehensive diagnostic testing that includes immunoassay (IgM and IgG), complement fixation, and immunodiffusion, refer to Coccidioides Antibodies Panel, CSF (3000061).
New York DOH Approval Status
Specimen Required
CSF.
Transfer 2 mL CSF to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.
Refrigerated.
Other body fluids. Contaminated, hemolyzed, xanthochromic, or severely lipemic specimens.
Mark specimens plainly as "acute" or "convalescent".
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Methodology
Enzyme-Linked Immunosorbent Assay (ELISA)
Performed
Sun-Sat
Reported
1-3 days
Reference Interval
Test Number |
Components |
Reference Interval |
---|---|---|
Coccidioides Antibody IgG ELISA, CSF | 0.2 IV or less | |
Coccidioides Antibody IgM ELISA, CSF | 0.2 IV or less |
Interpretive Data
Component | Interpretation |
---|---|
Coccidioides Antibodies IgG by Immunoassay, CSF | 0.2 IV or less Negative - No significant level of Coccidioides IgG antibody detected. 0.3 IV or greater Positive - Presence of IgG antibody to Coccidioides detected, suggestive of current or past infection. |
Coccidioides Antibodies IgM by Immunoassay, CSF | 0.2 IV or less Negative - No significant level of Coccidioides IgM antibody detected. 0.3 IV or greater Positive - Presence of IgM antibody to Coccidioides detected, suggestive of current or recent infection. |
FDA
Note
This immunoassay uses recombinant and native Coccidioides antigens, including CF and TP antigens.
Hotline History
CPT Codes
86635 x2
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3000062 | Coccidioides Antibody IgG ELISA, CSF | 16638-9 |
3000063 | Coccidioides Antibody IgM ELISA, CSF | 16639-7 |
Aliases
- CF
- Coccidioides immitis
- Coccidioidomycosis
- Precipitin
- TP
- Valley fever