Use to screen for the presence of coccidioidal IgG antibodies in CSF. Not recommended as a standalone test. For comprehensive diagnostic testing that includes immunoassay (IgM and IgG), complement fixation, and immunodiffusion, refer to Coccidioides Antibodies Panel, CSF (3000061).
Enzyme-Linked Immunosorbent Assay (ELISA)
New York DOH Approval Status
Transfer 1 mL CSF to an ARUP Standard Transport Tube. (Min: 0.3 mL). Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.
Other body fluids. Contaminated, hemolyzed, xanthochromic, or severely lipemic specimens.
Mark specimens plainly as acute or convalescent.
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
|0.2 IV or less||Negative - No significant level of Coccidioides IgG antibody detected.|
|0.3 IV or greater||Positive - Presence of IgG antibody to Coccidioides detected, suggestive of current or past infection.|
IgG antibodies usually appear by the third week of infection and may persist for years. Both tube precipitin (TP) and CF antigens are represented in the ELISA tests.
This immunoassay uses recombinant and native Coccidioides antigens, including CF and TP antigens.
|Component Test Code*||Component Chart Name||LOINC|
|3000062||Coccidioides Antibody IgG ELISA, CSF||16638-9|
- Coccidioides immitis
- Valley fever