Ordering Recommendation

Useful for general screening in contexts of compliance and/or abuse. A screen with reflex testing is the preferred method for ruling out tramadol exposure. For follow-up testing of a presumptive result, Tramadol and Metabolites, Urine, Quantitative (2002736) is preferred.

Mnemonic
TRAM RFX U
Methodology

Qualitative Enzyme Immunoassay/Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Sun-Sat

Reported

1-6 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Random urine.

Specimen Preparation

Transfer 4 mL urine with no additives or preservatives to an ARUP Standard Transport Tube. (Min: 2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Pharmaceutical preparation. Specimens exposed to repeated freeze/thaw cycles.

Remarks
Stability

Ambient: 1 week; Refrigerated: 10 days; Frozen: 8 months

Reference Interval

Screen Cutoff concentration 200 ng/mL

Interpretive Data

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration at which the screening test can detect a drug or metabolite varies. Specimens for which drugs or drug classes are detected by the screen are reflexed to a second, more specific technology (GC/MS and/or LC-MS/MS). The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use. 

Compliance Category

FDA

Note

If the specimen screens positive, then Confirmation/Quantitation by LC-MS/MS (ARUP test code 2002736) will be added to confirm result. Additional charges apply.

Hotline History
N/A
CPT Codes

80307; if reflexed, add 80373 (Reflexed Alt Code: G0480 )

Components
Component Test Code* Component Chart Name LOINC
2012212 Screen, Urine Interpretation 54247-2
2012298 Tramadol, Urn, Screen 19712-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • N-Desmethyltramadol
  • O-Desmethyltramadol
  • Ryzolt
  • Tramal
  • Ultracet
  • Ultram
Tramadol, Urine Screen with Reflex to Quantitation