Ordering Recommendation

Useful for general screening in contexts of compliance and/or abuse. A screen with reflex testing is the preferred method for ruling out fentanyl exposure. For follow-up testing of a presumptive result, Fentanyl and Metabolite, Urine Quantitative (0092570) is preferred.

Mnemonic
FENT RFX U
Methodology

Qualitative Enzyme Immunoassay/Quantitative Liquid Chromatography - Tandem Mass Spectrometry

Performed

Sun-Sat

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Random urine.

Specimen Preparation

Transfer 4 mL urine with no additives or preservatives in ARUP Standard Transport Tubes. (Min: 1 mL)

Storage/Transport Temperature

Room temperature.

Unacceptable Conditions

Specimens exposed to repeated freeze/thaw cycles. Samples collected in tubes with additives or preservatives.

Remarks
Stability

Ambient: 1 month; Refrigerated: 1 month; Frozen: 9 months

Reference Interval

Screen cutoff Concentration: 2 ng/mL

Interpretive Data

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration at which the screening test can detect a drug or metabolite varies. Specimens for which drugs or drug classes are detected by the screen are reflexed to a second, more specific technology (GC/MS and/or LC-MS/MS). The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note

If the specimen screens positive, then Confirmation/Quantitation by LC-MS/MS (ARUP test code 0092570) will be added to confirm result. Additional charges apply.

Hotline History
N/A
CPT Codes

80307; if reflexed, add 80354 (Reflexed Alt Code: G0480 )

Components
Component Test Code* Component Chart Name LOINC
2012212 Screen, Urine Interpretation 54247-2
2012285 Fentanyl, Urn, Screen 11235-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Actiq
  • Duragesic
  • Durogesic
  • Fentanyl and Metabolite
  • fentanyl and norfentanyl blood levels
  • Fentore
  • Innovar
  • Instanyl
  • Ionsys
  • norfentanyl
  • onsolis
  • sublimaze
Fentanyl , Urine Screen with Reflex to Quantitation