Ordering Recommendation

Useful for general screening in contexts of compliance and/or abuse. A screen with reflex testing is the preferred method for ruling out fentanyl exposure. For follow-up testing of a presumptive result, Fentanyl and Metabolite, Urine Quantitative (0092570) is preferred.

Mnemonic
FENT RFX U
Methodology

Qualitative Enzyme Immunoassay/Quantitative Liquid Chromatography - Tandem Mass Spectrometry

Performed

Sun-Sat

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Random urine.

Specimen Preparation

Transfer 4 mL urine with no additives or preservatives in ARUP Standard Transport Tubes. (Min: 1 mL)

Storage/Transport Temperature

Room temperature.

Unacceptable Conditions

Specimens exposed to repeated freeze/thaw cycles. Samples collected in tubes with additives or preservatives.

Remarks
Stability

Ambient: 1 month; Refrigerated: 1 month; Frozen: 9 months

Reference Interval

Screen cutoff Concentration: 2 ng/mL

Interpretive Data

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration at which the screening test can detect a drug or metabolite varies. Specimens for which drugs or drug classes are detected by the screen are reflexed to a second, more specific technology (GC/MS and/or LC-MS/MS). The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use.

Compliance Category

FDA

Note

If the specimen screens positive, then Confirmation/Quantitation by LC-MS/MS (ARUP test code 0092570) will be added to confirm result. Additional charges apply.

Hotline History
N/A
CPT Codes

80307; if reflexed, add 80354 (Reflexed Alt Code: G0480 )

Components
Component Test Code* Component Chart Name LOINC
2012212 Screen, Urine Interpretation 54247-2
2012285 Fentanyl, Urn, Screen 11235-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Actiq
  • Duragesic
  • Durogesic
  • Fentanyl and Metabolite
  • fentanyl and norfentanyl blood levels
  • Fentore
  • Innovar
  • Instanyl
  • Ionsys
  • norfentanyl
  • onsolis
  • sublimaze
Fentanyl , Urine Screen with Reflex to Quantitation