Ordering Recommendation

Useful for general screening in contexts of compliance and/or abuse. A screen with reflex testing is the preferred method for ruling out buprenorphine exposure. For follow-up testing of a presumptive result, Buprenorphine and Metabolites, Urine, Quantitative (2010092) is preferred.


Qualitative Enzyme Immunoassay/Quantitative Liquid Chromatography - Tandem Mass Spectometery




1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Random urine.

Specimen Preparation

Transfer 4 mL urine with no additives or preservatives to an ARUP Standard Transport Tube (Min: 2 mL)

Storage/Transport Temperature

Room temperature.

Unacceptable Conditions

Unknown fluids, pharmaceutical preparations, and breast milk. Specimens exposed to repeated freeze/thaw cycles.


Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 years

Reference Interval

Screen cutoff concentration: 5 ng/mL

Interpretive Data

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration at which the screening test can detect a drug or metabolite varies.  Specimens for which drugs or drug classes are detected by the screen are reflexed to a second, more specific technology (GC/MS and/or LC-MS/MS). The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use.

No compliance statements are in use for this test.


If the specimen screens positive, then Confirmation/Quantitation by LC-MS/MS (ARUP test code 2010092) will be added to confirm result. Additional charges apply.

Hotline History
CPT Codes

80307; if reflexed, add 80348 (Reflexed Alt Code: G0480 )

Component Test Code* Component Chart Name LOINC
2012212 Screen, Urine Interpretation 54247-2
2012274 Buprenorphine, Urn, Screen 3415-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Buprenex
  • Buprenorphine
  • Butrans
  • Glucuronide
  • Norbuprenorphine
  • Norbuprenorphine Glucuronide
  • Norspan
  • Suboxone
  • Temgesic
  • Vetergesic
Buprenorphine, Urine Screen with Reflex to Quantitation