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2011622
Alpha Globin (HBA1 and HBA2) Deletion/Duplication
HBA DD
Ordering Recommendation
Preferred first-tier genetic test for confirmation of suspected alpha thalassemia or alpha thalassemia trait. Use to detect common as well as rare and novel deletions or duplications of the alpha globin gene cluster.
New York DOH Approval Status
This test is New York state approved.
Specimen Required
Patient Preparation
Collect
Lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A or B)
Specimen Preparation
Transport 3 mL whole blood. (Min: 1 mL)
Storage/Transport Temperature
Refrigerated. Also acceptable: Ambient.
Unacceptable Conditions
Remarks
Stability
Room temperature: 1 week; Refrigerated: 1 month; Frozen: Unacceptable
Methodology
Multiplex Ligation-Dependent Probe Amplification (MLPA)
Performed
Varies
Reported
7-14 days
Reference Interval
By report
Interpretive Data
Refer to report.
Compliance Category
Laboratory Developed Test (LDT)
Note
Hotline History
N/A
CPT Codes
81269
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2011623 | Alpha Globin (HBA1/2) DelDup Specimen | 31208-2 |
| 2011624 | Alpha Globin (HBA1/2) DelDup Interp | 90040-7 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- Alpha globin mutations
- Alpha globin gene analysis
- Alpha thalassemia
- A globin
Alpha Globin (HBA1 and HBA2) Deletion/Duplication
