Ordering Recommendation

Essential first-line test for suspected acute porphyria in adults. Use in determining metabolic response to IV hematin.

Mnemonic
UPBGQTRAND
Methodology

Quantitative Ion Exchange Chromatography/Spectrophotometry

Performed

Mon-Fri

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Random urine.

Specimen Preparation

Protect from light. Transfer an 8 mL aliquot from a well-mixed collection to ARUP Amber Transport Tubes. (Min: 3.5 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Body fluids other than urine.

Remarks
Stability

Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month

Reference Interval
Components
Reference Interval
Porphobilinogen (PBG), Urine-per volume 0.0-8.8 µmol/L
Porphobilinogen, Rndm Urn-ratio to CRT No reference interval (mg/g crt)

Interpretive Data



Compliance Category

Laboratory Developed Test (LDT)

Note

Appropriate test to rule out acute intermittent porphyria (AIP) and other acute attacks of other types of porphyrias associated with neurologic and/or psychiatric symptoms.

Hotline History
N/A
CPT Codes

84110

Components
Component Test Code* Component Chart Name LOINC
0020207 Creatinine, Urine - per volume 2161-8
0080262 Porphobilinogen (PBG), Urine -per volume 2811-8
2011477 Porphobilinogen, Rndm Urn-ratio to CRT 13797-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • PBG, Quantitative
  • Porphobilinogen
  • Watson-Schwartz Test
Porphobilinogen (PBG), Random Urine