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Porphobilinogen (PBG), Random Urine
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Ordering Recommendation
Essential first-line test for suspected acute porphyria in adults. Use in determining metabolic response to IV hematin.
Mnemonic
Methodology
Quantitative Ion Exchange Chromatography/Spectrophotometry
Performed
Mon-Fri
Reported
1-4 days
New York DOH Approval Status
Specimen Required
Random urine.
Protect from light. Transfer an 8 mL aliquot from a well-mixed collection to ARUP Amber Transport Tubes. (Min: 3.5 mL)
Frozen.
Body fluids other than urine.
Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month
Reference Interval
| Components |
Reference Interval |
|---|---|
| Porphobilinogen (PBG), Urine-per volume | 0.0-8.8 µmol/L |
| Porphobilinogen, Rndm Urn-ratio to CRT | No reference interval (mg/g crt) |
Interpretive Data
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Appropriate test to rule out acute intermittent porphyria (AIP) and other acute attacks of other types of porphyrias associated with neurologic and/or psychiatric symptoms.
Hotline History
CPT Codes
84110
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0020207 | Creatinine, Urine - per volume | 2161-8 |
| 0080262 | Porphobilinogen (PBG), Urine -per volume | 2811-8 |
| 2011477 | Porphobilinogen, Rndm Urn-ratio to CRT | 13797-6 |
Aliases
- PBG, Quantitative
- Porphobilinogen
- Watson-Schwartz Test
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