Essential first-line test for suspected acute porphyria in adults. Use in determining metabolic response to IV hematin.
Quantitative Ion Exchange Chromatography/Spectrophotometry
New York DOH Approval Status
Random or 24-hour urine. Refrigerate 24-hour specimens during collection.
Protect from light. Transfer 8 mL aliquot from a random or well-mixed 24-hour collection to ARUP Amber Transport Tubes. (Min: 3.5 mL) Record total volume and collection time interval on transport tube and test request form.
Body fluids other than urine.
Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month
|Porphobilinogen (PBG), Urine -per volume||0.0-8.8 µmol/L|
|Porphobilinogen, Urine - per 24h||0.0-11.0 µmol/d|
|0020473||Creatinine, Urine - per 24h||
Per 24h calculations are provided to aid interpretation for collections with a duration of 24 hours and an average daily urine volume. For specimens with notable deviations in collection time or volume, ratios of analytes to a corresponding urine creatinine concentration may assist in result interpretation.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Appropriate test to rule out acute intermittent porphyria (AIP) and other acute attack types of porphyrias associated with neurologic and/or psychiatric symptoms.
|Component Test Code*||Component Chart Name||LOINC|
|0020207||Creatinine, Urine - per volume||2161-8|
|0020208||Creatinine, Urine - per 24h||2162-6|
|0080261||Porphobilinogen, Urine - per 24h||14882-5|
|0080262||Porphobilinogen (PBG), Urine -per volume||2811-8|
- PBG, Quantitative
- Watson-Schwartz Test