Essential first-line test for suspected acute porphyria in adults. Use in determining metabolic response to IV hematin.
Quantitative Ion Exchange Chromatography/Spectrophotometry
Random or 24-hour urine. Refrigerate 24-hour specimens during collection.
Protect from light. Transfer 8 mL aliquot from a random or well-mixed 24-hour collection to ARUP Amber Transport Tubes. (Min: 3.5 mL) Record total volume and collection time interval on transport tube and test request form.
Body fluids other than urine.
Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month
|Porphobilinogen (PBG), Urine -per volume||0.0-8.8 µmol/L|
|Porphobilinogen, Urine - per 24h||0.0-11.0 µmol/d|
|0020473||Creatinine, Urine - per 24h||
Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Appropriate test to rule out acute intermittent porphyria (AIP) and other acute attack types of porphyrias associated with neurologic and/or psychiatric symptoms.
|Component Test Code*||Component Chart Name||LOINC|
|0020207||Creatinine, Urine - per volume||2161-8|
|0020208||Creatinine, Urine - per 24h||2162-6|
|0080261||Porphobilinogen, Urine - per 24h||14882-5|
|0080262||Porphobilinogen (PBG), Urine -per volume||2811-8|
- PBG, Quantitative
- Watson-Schwartz Test