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Antiviral Susceptibility, Herpes Simplex Virus, Acyclovir
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Ordering Recommendation
Detect herpes simplex virus (HSV) resistance to acyclovir.
Mnemonic
Methodology
Cell Culture, Susceptibility
Performed
Wed
Reported
2-3 weeks
New York DOH Approval Status
Specimen Required
Isolate from cell culture (3-4+ positivity).
Isolate from cell culture (3-4+ positivity). Place each specimen in an individually sealed bag.
Room temperature. Also acceptable: Refrigerated and frozen on dry ice.
Ambient: 48 hours; Refrigerated: 72 hours; Frozen at -70°C: 1 month
Reference Interval
Less than 2 µg/mL
Interpretive Data
A value of greater than or equal to 2 µg/mL suggests resistance.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
A processing fee will be billed for isolates that fail to grow to 3-4+ positivity as indicated in the specimen requirements. For specimens other than isolates (swabs) refer to Herpes Simplex Virus Culture (Test Number 0065005).
Hotline History
CPT Codes
87252; 87253
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2010868 | Acyclovir Interpretation | 73574-6 |
| 2010978 | Acyclovir IC50 Value | 9416-9 |
Aliases
- Acyclovir Resistance HSV
- Drug Resistance
- Herpes Simplex Types 1 and 2 virus Phenotyping
- Phenotyping for Acyclovir
- Zovirax Resistance
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