Preferred test to assess for hereditary form of cardiomyopathy or arrhythmia.
Massively Parallel Sequencing
New York DOH Approval Status
Lavender or pink (EDTA) or yellow (ACD solution A or B).
Transport 3 mL whole blood. (Min: 3 mL)
Serum or plasma; grossly hemolyzed or frozen specimens; saliva, buccal brush, or swab; FFPE tissue.
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
Refer to report.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Counseling and informed consent are recommended for genetic testing. Consent forms are available online.
Laboratory Developed Test (LDT)
Genes Tested: ABCC9; ACTC1; ACTN2; AGL; ALMS1; ALPK3; BAG3; BRAF*; CACNA1C; CALM1*; CALM2; CALM3; CASQ2; CRYAB; CSRP3*; DES*; DMD; DOLK; DSC2; DSG2; DSP; EMD; FHL1*; FKTN*; FLNC*; GAA; GLA; HCN4; HRAS; JPH2; JUP; KCNE1; KCNE2; KCNH2*; KCNJ2; KCNQ1; KRAS; LAMP2; LDB3; LMNA; MAP2K1; MAP2K2*; MYBPC3; MYH6*; MYH7*; MYL2; MYL3; NEXN; NKX2-5; NRAS; PKP2*; PLN; PRDM16; PRKAG2*; PTPN11**; RAF1*; RBM20; RIT1*; RYR2; SCN5A; SOS1*; TAFAZZIN; TCAP; TECRL*; TMEM43; TNNC1; TNNI3; TNNI3K; TNNT2; TPM1*; TRDN*; TTN*; TTR; VCL
*One or more exons are not covered by sequencing and/or deletion/duplication analysis for the indicated gene; see Additional Technical Information.
**Deletion/duplication detection is not available for this gene.
81403; 81404; 81405; 81406; 81407; 81408; 81479; 81414
|Component Test Code*||Component Chart Name||LOINC|
|2010184||Cardiomyopathy/Arrhythmia Panel Specimen||31208-2|
|2010187||Cardiomyopathy/Arrhythmia Panel Interp||41103-3|
- Arrhythmogenic right ventricular cardiomyopathy (ARVC)
- arrhythmogenic right ventricular dysplasia (ARVD)
- atrial septal defect with or without AV conduction defects
- Brugada syndrome (BrS)
- catecholaminergic polymorphic ventricular tachycardia (CPVT)
- dilated cardiomyopathy (DCM)
- familial dilated cardiomyopathy (FDC)
- familial polymorphic cardiomyopathy (FPVT)
- hypertrophic cardiomyopathy (HCM)
- Jervell and Lange-Nielsen syndrome
- left ventricular noncompaction (LVNC)
- long QT syndrome (LQTS)
- Noonan syndrome
- short QT syndrome (SQTS)
- sick sinus syndrome
- Uhl anomaly