Ordering Recommendation

Use to monitor heparan sulfate (total disaccharides and nonreducing ends) excretion for MPS Type II patients who are on therapy.

Mnemonic
MPS2 QNT U
Methodology

Quantitative Liquid Chromatography/Tandem Mass Spectrometry

Performed

Mon

Reported

2-3 weeks

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation

Morning void is preferred.

Collect

Urine.

Specimen Preparation

Transfer 2 mL urine to ARUP Standard Transport Tube and freeze immediately. (Min: 1 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Refrigerated specimens received in lab more than 24 hours after collection.

Remarks
Stability

Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 1 month (avoid repeated freeze/thaw cycles)

Reference Interval

By report

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

83864

Components
Component Test Code* Component Chart Name LOINC
2009280 MPS II Urine Interpretation
2009281 MPS II Creatinine, Urine
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Mucopolysaccharidosis Type II, Total HS and NRE (Sensi-Pro(R)) Quantitative, Urine