Mucopolysaccharidoses Type 1/2, Total Heparan Sulfate and NRE (Sensi-Pro®) Quantitative, Urine
Ordering Recommendation
Aids in the diagnosis and monitoring of patients with MPS Type 1 or Type 2.
Mnemonic
Methodology
Liquid Chromatography-Tandem Mass Spectrometry
Performed
Varies
Reported
14-21 days
New York DOH Approval Status
Specimen Required
First catch urine is preferred.
Urine
Transfer 2mL urine to ARUP Standard transport Tube and freeze immediately. (Min 1 mL)
Frozen
Specimens containing preservatives or heparin
N/A
Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month (avoid repeated freeze /thaw cycles)
Reference Interval
By report
Interpretive Data
Refer to report.
Total Heparan Sulfate, Urine is a sum of the internal disaccharides D0A0 and D0S0.
NRE = Non Reducing End
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Hotline History
Hotline History
CPT Codes
83864
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3003553 | MPS 1/2 Creatinine, Urine | |
3003554 | MPS 1/2 Urine Interpretation | |
3003559 | Total Heparan Sulfate, Urine | |
3003561 | I0S0 (MPS 1 NRE), Urine | |
3003563 | I0S6 (MPS 1 NRE), Urine | |
3003565 | I2S0 (MPS 2 NRE), Urine | |
3005210 | EER MPS 1/2 Urine | 11502-2 |
Aliases
- heparan sulfate
- HS non reducing end assay
- MPS 1
- MPS 2
- MPS I
- MPS II
- MPS Type 1
- MPS Type 2
- Urine mucopolysaccharides total and NRE
- Urine total and NRE mucopolysaccharides