Ordering Recommendation

First-line test to diagnose acute babesiosis. Detects nucleic acid from Babesia microti, and detects but does not differentiate between B. duncani,  B. divergens, and Babesia strains MO-1 and EU-1. Blood smears are also appropriate to diagnose and monitor babesiosis; refer to Parasites Smear (Giemsa Stain), Blood (0049025). If also investigating anaplasmosis or ehrlichiosis, consider Tick-Borne Disease Panel by PCR, Blood (2008670).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Lavender (EDTA) or pink (K2EDTA).

Specimen Preparation

Transport 1 mL whole blood. (Min: 0.6 mL)

Storage/Transport Temperature


Unacceptable Conditions

Serum, plasma, and heparinized specimens.


Ambient: 24 hours; Refrigerated: 1 week; Frozen: 14 days


Qualitative Polymerase Chain Reaction




1-3 days

Reference Interval

Interpretive Data

A negative result does not rule out the presence of PCR inhibitors in the patient specimen or test-specific nucleic acid in concentrations below the level of detection by this test.

Compliance Category

Laboratory Developed Test (LDT)


This test detects and speciates B. microti. The nucleic acid from B. duncani, B. divergens, strain MO-1, and strain EU-1 will be detected by this test but cannot be differentiated.

Hotline History


CPT Codes

87469; 87798


Component Test Code* Component Chart Name LOINC
2008666 Babesia species by PCR 88233-2
2008668 Babesia microti by PCR 21089-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


Babesia Species by PCR