Optimize drug therapy and monitor patient adherence. This test detects risperidone (parent) AND paliperidone (9-hydroxyrisperidone, metabolite). For paliperidone (9-hydroxyrisperidone) only, order Paliperidone, Serum or Plasma (2007949).
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Mon, Wed, Sat
Pre-dose (trough) draw - At steady state concentration.
Lavender (EDTA), pink (K2EDTA) or plain red.
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).
Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: 2 months
|Therapeutic range||Not well established|
|Total (Risperidone and Metabolite)||20-60 ng/mL|
|Toxic range||Not well established|
Adverse effects to risperidone therapy may include headache, nausea, dizziness, tachycardia, orthostatic hypotension and dyskinesia.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
80342 (Alt code: G0480)
|Component Test Code*||Component Chart Name||LOINC|
|2007953||9 OH Risperidone Serum/Plasma||9383-1|
|2007954||Total Risper/9 OH Risper||9394-8|
- risperdal blood level
- risperidone blood level