Ordering Recommendation

Useful for general screening in the assessment of ethanol exposure in the contexts of compliance and/or abuse. A screen with reflex testing is the preferred method for ruling out ethanol exposure. For follow-up testing of a presumptive result, Ethyl Glucuronide and Ethyl Sulfate, Urine, Quantitative (2007909) is preferred. Results do not accurately correlate with amount or frequency of ethanol use.

Mnemonic
ETG SCR
Methodology

Qualitative Enzyme Immunoassay/Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Sun-Sat

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Random urine.

Specimen Preparation

Transfer 4 mL urine with no additives or preservatives to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks
Stability

Ambient: 20 days; Refrigerated: 20 days; Frozen: 20 days

Reference Interval

Screen cutoff concentration: 500 ng/mL

Interpretive Data

Ethyl glucuronide is a direct metabolite of ethanol and can be detected up to 80 hours in urine after ethanol ingestion. The cutoff for positive by immunoassay is set at 500 ng/mL. A positive result will be confirmed by liquid chromatography tandem mass spectrometry (LC-MS/MS).

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

80307; if reflexed, add 80321 (Reflexed Alt Code: G0480 )

Components
Component Test Code* Component Chart Name LOINC
2007913 Ethyl Glucuronide Screen w/Rflx, Urine 58375-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Ethyl Glucuronide Screen with Reflex to Confirmation, Urine