Ordering Recommendation

May be useful in the assessment of ethanol exposure in the contexts of compliance and/or abuse. For general screening, Ethyl Glucuronide Screen with Reflex to Quantitation, Urine (2007912) is preferred. Results do not accurately correlate with amount or frequency of ethanol use.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Random urine.

Specimen Preparation

Transfer 4 mL urine with no additives or preservatives to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature


Unacceptable Conditions

Ambient: 20 days; Refrigerated: 20 days; Frozen: 20 days


Quantitative Liquid Chromatography-Tandem Mass Spectrometry


Sun, Tue-Sat


1-7 days

Reference Interval

Interpretive Data

Ethyl glucuronide (EtG) and Ethyl Sulfate (EtS) are direct metabolites of ethanol. EtG and EtS can be detected up to 80 hours in urine after ethanol ingestion and the presence of both metabolites can be used as markers for recent alcohol use. The presence of EtG, alone in urine, is not a unique marker of ethanol ingestion. False positive EtG results can occur from microbial formation or from fermentation and false negative EtG results can occur from bacterial degradation. The analytical measurement range is 100-10,000 ng/mL.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes

80321 (Alt code: G0480)


Component Test Code* Component Chart Name LOINC
2007910 Ethyl Glucuronide, Urn, Quant 58378-1
2007911 Ethyl Sulfate, Urn, Quant 58425-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


Ethyl Glucuronide and Ethyl Sulfate, Urine, Quantitative