Ordering Recommendation

May be useful in the assessment of ethanol exposure in the contexts of compliance and/or abuse. For general screening, Ethyl Glucuronide Screen with Reflex to Quantitation, Urine (2007912) is preferred. Results do not accurately correlate with amount or frequency of ethanol use.

Mnemonic
CDCO ETG/S
Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Sun, Tue-Wed, Fri-Sat

Reported

1-6 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Random urine.

Specimen Preparation

Transfer 4 mL urine with no additives or preservatives to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks
Stability

Ambient: 20 days; Refrigerated: 20 days; Frozen: 20 days

Reference Interval
Interpretive Data

Ethyl glucuronide (EtG) and Ethyl Sulfate (EtS) are direct metabolites of ethanol. EtG and EtS can be detected up to 80 hours in urine after ethanol ingestion and the presence of both metabolites can be used as markers for recent alcohol use. The presence of EtG, alone in urine, is not a unique marker of ethanol ingestion. False positive EtG results can occur from microbial formation or from fermentation and false negative EtG results can occur from bacterial degradation. The analytical measurement range is 100-10,000 ng/mL.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

80321 (Alt code: G0480)

Components
Component Test Code* Component Chart Name LOINC
2007910 Ethyl Glucuronide, Urn, Quant 58378-1
2007911 Ethyl Sulfate, Urn, Quant 58425-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Ethyl Glucuronide and Ethyl Sulfate, Urine, Quantitative