Ethyl Glucuronide and Ethyl Sulfate, Urine, Quantitative
Ordering Recommendation
May be useful in the assessment of ethanol exposure in the contexts of compliance and/or abuse. For general screening, Ethyl Glucuronide Screen with Reflex to Quantitation, Urine (2007912) is preferred. Results do not accurately correlate with amount or frequency of ethanol use.
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun, Tue-Sat
Reported
1-7 days
New York DOH Approval Status
Specimen Required
Random urine.
Transfer 4 mL urine with no additives or preservatives to an ARUP Standard Transport Tube. (Min: 1 mL)
Refrigerated.
Ambient: 20 days; Refrigerated: 20 days; Frozen: 20 days
Reference Interval
Interpretive Data
Ethyl glucuronide (EtG) and Ethyl Sulfate (EtS) are direct metabolites of ethanol. EtG and EtS can be detected up to 80 hours in urine after ethanol ingestion and the presence of both metabolites can be used as markers for recent alcohol use. The presence of EtG, alone in urine, is not a unique marker of ethanol ingestion. False positive EtG results can occur from microbial formation or from fermentation and false negative EtG results can occur from bacterial degradation. The analytical measurement range is 100-10,000 ng/mL.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Hotline History
Hotline History
CPT Codes
80321 (Alt code: G0480)
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
2007910 | Ethyl Glucuronide, Urn, Quant | 58378-1 |
2007911 | Ethyl Sulfate, Urn, Quant | 58425-0 |