Ordering Recommendation

Recommended for the assessment of iodine nutritional status. This test reports total iodine from all iodine-containing species present in the specimen but does not determine the chemical form (species) of the iodine present. For determination of iodine excess and monitoring iodine overload in patients administered iodine-containing medications, refer to Iodine, Serum (2007463).

Mnemonic
IODINE U
Methodology

Quantitative Inductively Coupled Plasma-Mass Spectrometry

Performed

Tues, Thu, Sat

Reported

1-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications for 48 hours (upon the advice of their physician). In addition, the administration of iodine-based contrast media and drugs containing Iodine may yield elevated results. Specimen must be collected in a plastic container and should be refrigerated after collection.

Collect

24-hour or random urine collection.

Specimen Preparation

Transfer an 8 mL aliquot from a well-mixed collection to ARUP Trace Element-Free Tubes (ARUP supply #43116) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Acid preserved urine. Specimens collected within 72 hours after administration of iodinated or gadolinium-based contrast media. Specimens contaminated with blood or fecal material. Specimens transported in non-trace element-free transport tube (with the exception of the original device).

Remarks

Record the total volume and collection time interval on transport tube and on test request form.

Stability

Ambient: 2 months; Refrigerated: 2 months; Frozen: 2 months

Reference Interval
Test Number
Components
Reference Interval
  Iodine, Urine - per volume
Age
16 years and older 26.0-705.0 ug/L

  Iodine, Urine - per 24h
Age
16 years and older 93.0 - 1125.0 ug/d

Iodine per gram of Creatinine 35.0-540.0 µg/g crt
0020473 Creatinine, Urine - per 24h
Age
Male
Female
3-8 years 140-700 mg/d 140-700 mg/d
9-12 years 300-1300 mg/d 300-1300 mg/d
13-17 years 500-2300 mg/d 400-1600 mg/d
18-50 years 1000-2500 mg/d 700-1600 mg/d
51-80 years 800-2100 mg/d 500-1400 mg/d
81 years and older 600-2000 mg/d 400-1300 mg/d

Interpretive Data

Values greater than 1000 µg/L may indicate dietary excess, but more frequently suggest recent drug or contrast media exposure.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

83018

Components
Component Test Code* Component Chart Name LOINC
0020207 Creatinine, Urine - per volume 2161-8
0020208 Creatinine, Urine - per 24h 2162-6
0097110 Total Volume 19153-6
0097111 Hours Collected 30211-7
2007466 Iodine, Urine - per volume 26842-5
2007467 Iodine, Urine - per 24h 2492-7
2007468 Iodine, per gram of CRT 55928-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • I urine
  • Iodide urine
  • Urinary Free Iodine
  • Urinary Iodine
Iodine, Urine