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Iodine, Urine
Ordering Recommendation
Recommended for the assessment of iodine nutritional status. This test reports total iodine from all iodine-containing species present in the specimen but does not determine the chemical form (species) of the iodine present. For determination of iodine excess and monitoring iodine overload in patients administered iodine-containing medications, refer to Iodine, Serum (2007463).
New York DOH Approval Status
Specimen Required
Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications for 48 hours (upon the advice of their physician). In addition, the administration of iodine-based contrast media and drugs containing Iodine may yield elevated results. Specimen must be collected in a plastic container and should be refrigerated after collection.
24-hour or random urine collection.
Transfer an 8 mL aliquot from a well-mixed collection to ARUP Trace Element-Free Tubes (ARUP supply #43116) available online through eSupply using ARUP Connect(TM) or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL)
Refrigerated.
Acid preserved urine. Specimens collected within 72 hours after administration of iodinated or gadolinium-based contrast media. Specimens contaminated with blood or fecal material. Specimens transported in non-trace element-free transport tube (with the exception of the original device).
Record the total volume and collection time interval on transport tube and on test request form.
Ambient: 2 months; Refrigerated: 2 months; Frozen: 2 months
Methodology
Quantitative Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Performed
Tue, Thu, Sat
Reported
1-5 days
Reference Interval
| Test Number |
Components |
Reference Interval |
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Creatinine, Urine - per 24h |
|
||||||||||||||||||||||
| Iodine, Urine - per volume | 16 years and older: 26.0-705.0 microg/L | ||||||||||||||||||||||
| Iodine, Urine - per 24h | 16 years and older: 93.0-1125.0 microg/d | ||||||||||||||||||||||
| Iodine, Urine - ratio to CRT | 35.0-540.0 microg/g CRT |
Interpretive Data
Values greater than 1000 ug/L may indicate dietary excess, but more frequently suggest recent drug or contrast media exposure.
Elevated results may be due to skin or collection-related contamination, including the use of collection containers that are not certified to be trace element-free. If an elevated result is suspected to be due to contamination, confirmation with a second specimen collected in a certified trace element-free container is recommended.
Methodology: Inductively Coupled Plasma - Mass Spectrometry (ICP-MS)
Per 24h calculations are provided to aid interpretation for collections with a duration of 24 hours and an average daily urine volume. For specimens with notable deviations in collection time or volume, ratios of analytes to a corresponding urine creatinine concentration may assist in result interpretation.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Hotline History
Hotline History
CPT Codes
83018
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0020207 | Creatinine, Urine - per volume | 35674-1 |
| 0020208 | Creatinine, Urine - per 24h | 2162-6 |
| 0097110 | Total Volume | 19153-6 |
| 0097111 | Hours Collected | 30211-7 |
| 2007466 | Iodine, Urine - per volume | 26842-5 |
| 2007467 | Iodine, Urine - per 24h | 2492-7 |
| 2007468 | Iodine, Urine - ratio to CRT | 55928-6 |
Aliases
- I urine
- Iodide urine
- Urinary Free Iodine
- Urinary Iodine
