Ordering Recommendation

Not recommended as a stand-alone test. Japanese Encephalitis Virus Antibodies, IgG and IgM by ELISA (2005689) is preferred.

Mnemonic
JPN G
Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Thu

Reported

1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Storage/Transport Temperature

Refrigerated

Unacceptable Conditions

Contaminated or heat-inactivated specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 months (avoid repeated freeze/thaw cycles).

Reference Interval

Effective May 21, 2018

Japanese Encephalitis Virus Antibody, IgG by ELISA
1.9 IV or less Negative - No significant level of detectable Japanese encephalitis virus (JEV) IgG antibody.
2.0 - 5.0 IV Equivocal - Questionable presence of JEV IgG antibody. Repeat testing in 10-14 days may be helpful.
5.1 IV or greater Positive - JEV IgG antibody detected, which may indicate a current or past infection.

Interpretive Data

Patients in the early stage of JEV infection may not have a detectable level of IgG antibody; IgG response may take several days to several weeks to develop. In the absence of detectable IgG antibody, testing for IgM-class antibody is strongly recommended. A positive result (5.1 IV or greater) indicates the presence of IgG antibody to a Flavivirus in the Japanese encephalitis serogroup or the dengue virus serogroup. Cross-species plaque reduction neutralization tests on paired acute and convalescent sera are an acceptable means of determining the Flavivirus causing the antibody production.

Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

86790

Components
Component Test Code* Component Chart Name LOINC
2005688 Japanese Encephalitis Virus Antibody IgG 7934-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • JE Virus IgG
Japanese Encephalitis Virus Antibody, IgG by ELISA