Ordering Recommendation

Not recommended as a stand-alone test. Japanese Encephalitis Virus Antibodies, IgG and IgM by ELISA (2005689) is preferred.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Serum separator tube

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Storage/Transport Temperature


Unacceptable Conditions

Contaminated or heat-inactivated specimens.


After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 months (avoid repeated freeze/thaw cycles).


Semi-Quantitative Enzyme-Linked Immunosorbent Assay




1-8 days

Reference Interval

Test Number
Reference Interval
  Japanese Encephalitis Virus Antibody IgG 5.0 IV or less

Interpretive Data

Patients in the early stage of JEV infection may not have a detectable level of IgG antibody; IgG response may take several days to several weeks to develop. In the absence of detectable IgG antibody, testing for IgM-class antibody is strongly recommended. A positive result (5.1 IV or greater) indicates the presence of IgG antibody to a Flavivirus in the Japanese encephalitis serogroup or the dengue virus serogroup. Cross-species plaque reduction neutralization tests on paired acute and convalescent sera are an acceptable means of determining the Flavivirus causing the antibody production.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Unit Of Measure
Japanese Encephalitis Virus Antibody IgG 1.9 IV or less
2.0 - 5.0 IV
5.1 IV or greater
Negative - No significant level of detectable Japanese encephalitis virus (JEV) IgG antibody.
Equivocal - Questionable presence of JEV IgG antibody. Repeat testing in 10-14 days may be helpful.
Positive - JEV IgG antibody detected, which may indicate a current or past infection.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
2005688 Japanese Encephalitis Virus Antibody IgG 7934-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • JE Virus IgG
Japanese Encephalitis Virus Antibody, IgG by ELISA