Not recommended as a stand-alone test. Japanese Encephalitis Virus Antibodies, IgG and IgM by ELISA (2005689) is preferred.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Serum separator tube
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)
Contaminated or heat-inactivated specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 months (avoid repeated freeze/thaw cycles).
Effective May 21, 2018
|Japanese Encephalitis Virus Antibody, IgG by ELISA
|1.9 IV or less||Negative - No significant level of detectable Japanese encephalitis virus (JEV) IgG antibody.|
|2.0 - 5.0 IV||Equivocal - Questionable presence of JEV IgG antibody. Repeat testing in 10-14 days may be helpful.|
|5.1 IV or greater||Positive - JEV IgG antibody detected, which may indicate a current or past infection.|
Patients in the early stage of JEV infection may not have a detectable level of IgG antibody; IgG response may take several days to several weeks to develop. In the absence of detectable IgG antibody, testing for IgM-class antibody is strongly recommended. A positive result (5.1 IV or greater) indicates the presence of IgG antibody to a Flavivirus in the Japanese encephalitis serogroup or the dengue virus serogroup. Cross-species plaque reduction neutralization tests on paired acute and convalescent sera are an acceptable means of determining the Flavivirus causing the antibody production.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|2005688||Japanese Encephalitis Virus Antibody IgG||7934-3|
- JE Virus IgG