Not recommended as a stand-alone test. Japanese Encephalitis Virus Antibodies, IgG and IgM by ELISA (2005689) is preferred.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Serum separator tube
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)
Contaminated or heat-inactivated specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 months (avoid repeated freeze/thaw cycles).
Effective May 21, 2018
|Japanese Encephalitis Virus Antibody, IgG by ELISA
|1.9 IV or less||Negative - No significant level of detectable Japanese encephalitis virus (JEV) IgG antibody.|
|2.0 - 5.0 IV||Equivocal - Questionable presence of JEV IgG antibody. Repeat testing in 10-14 days may be helpful.|
|5.1 IV or greater||Positive - JEV IgG antibody detected, which may indicate a current or past infection.|
Patients in the early stage of JEV infection may not have a detectable level of IgG antibody; IgG response may take several days to several weeks to develop. In the absence of detectable IgG antibody, testing for IgM-class antibody is strongly recommended. A positive result (5.1 IV or greater) indicates the presence of IgG antibody to a Flavivirus in the Japanese encephalitis serogroup or the dengue virus serogroup. Cross-species plaque reduction neutralization tests on paired acute and convalescent sera are an acceptable means of determining the Flavivirus causing the antibody production.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|2005688||Japanese Encephalitis Virus Antibody IgG||7934-3|
- JE Virus IgG