Use to detect presence of Japanese encephalitis-related IgG and IgM antibodies in individuals with evidence of acute encephalitis syndrome (AES) who have recently traveled to or resided in an endemic country in Asia or the western Pacific. Patient's travel history is necessary to aid in test interpretation. Testing should also be considered for other arthropod-borne viruses with similar symptomology based on clinical presentation and travel history.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
New York DOH Approval Status
Serum separator tube
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)
Contaminated or heat-inactivated specimens
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 months (avoid repeated freeze/thaw cycles)
|Japanese Encephalitis Virus Antibody IgM||6.0 IV or less|
|Japanese Encephalitis Virus Antibody IgG||5.0 IV or less|
Refer to report
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
|Japanese Encephalitis Virus Antibody, IgG by ELISA||1.9 IV or less: Negative - No significant level of detectable Japanese encephalitis virus (JEV) IgG antibody.
2.0 - 5.0 IV: Equivocal - Questionable presence of JEV IgG antibody. Repeat testing in 10-14 days may be helpful.
5.1 IV or greater: Positive - JEV IgG antibody detected, which may indicate a current or past infection.
|Japanese Encephalitis Virus Antibody, IgM by ELISA||3.9 IV or less: Negative - No significant level of detectable Japanese encephalitis virus (JEV) IgM antibody.
4.0 -6.0 IV: Equivocal - Questionable presence of JEV IgM antibody. Repeat testing in 10-14 days may be helpful.
6.1 IV or greater: Positive - JEV IgM antibody detected, which may indicate a current or recent infection. A low IgM antibody level may occasionally persist for more than 12 months post-infection.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|2005686||Japanese Encephalitis Virus Antibody IgM||63562-3|
|2005688||Japanese Encephalitis Virus Antibody IgG||7934-3|
- JE Virus Antibodies
- JE Virus IgG, IgM