Ordering Recommendation

Not recommended as a stand-alone test. Japanese Encephalitis Virus Antibodies, IgG and IgM by ELISA (2005689) is preferred.


Semi-Quantitative Enzyme-Linked Immunosorbent Assay




1-8 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Serum separator tube

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Storage/Transport Temperature


Unacceptable Conditions

Contaminated or heat-inactivated specimens


After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 months (avoid repeated freeze/thaw cycles)

Reference Interval

Effective January 17, 2012

Japanese Encephalitis Virus Antibody, IgM by ELISA
3.9 IV or less Negative - No significant level of detectable Japanese encephalitis virus (JEV) IgM antibody.
4.0 -6.0 IV Equivocal - Questionable presence of JEV IgM antibody. Repeat testing in 10-14 days may be helpful.
6.1 IV or greater Positive - JEV IgM antibody detected, which may indicate a current or recent infection. A low IgM antibody level may occasionally persist for more than 12 months post-infection.

Interpretive Data

A positive result (6.1 IV or greater) indicates the presence of IgM antibody to a flavivirus in the Japanese encephalitis serogroup or the dengue virus serogroup. The best evidence of current infection is a significant change on two appropriately timed specimens with both tests performed in the same laboratory at the same time.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
2005686 Japanese Encephalitis Virus Antibody IgM 63562-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • JE Virus IgM
Japanese Encephalitis Virus Antibody, IgM by ELISA