Ordering Recommendation

Useful for general screening in contexts of compliance and/or abuse. A screen with reflex testing is the preferred method for ruling out opiate exposure. For follow-up testing of a presumptive result, Opiates, Urine, Quantitative (0090364) is preferred.




Qualitative Enzyme Immunoassay/Quantitative Liquid Chromatography-Tandem Mass Spectrometry




1-4 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Random urine.

Specimen Preparation

Transfer 4 mL urine with no additives or preservatives to an ARUP Standard Transport Tube. (Min: 2 mL)

Storage/Transport Temperature


Unacceptable Conditions

Specimens exposed to repeated freeze/thaw cycles.


Ambient: 1 week; Refrigerated: 1 month; Frozen: 1 month

Reference Interval

Effective May 16, 2011

Screen cutoff concentration: 100 ng/mL

Interpretive Data

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration at which the screening test can detect a drug or metabolite varies. Specimens for which drugs or drug classes are detected by the screen are reflexed to a second, more-specific technology (GC/MS and/or LC-MS/MS). The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use.

Compliance Category



This test detects oxycodone and oxymorphone. The confirmation test detects and quantifies morphine, codeine, hydrocodone, hydromorphone, 6-monoacetylmorphine, oxycodone and oxymorphone.

If the specimen screens positive, then Confirmation/Quantitation by LC-MS/MS (ARUP test 0090364) will be added to confirm result. Additional charges apply.

For detection of morphine, hydrocodone, and similar compounds, see Opiates Screen with Reflex to Confirmation, Urine (ARUP test code 2005093).

Compare to Oxycodone, w/ Confirmation w/ medMATCH, Urine.

Hotline History


CPT Codes

80307; if reflexed, add 80361; 80365 (Reflexed Alt Code: G0480 )


Component Test Code* Component Chart Name LOINC
2005102 Oxycodone/Oxymorphone, Urn, Screen 58430-0
2012212 Screen, Urine Interpretation 54247-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


Oxycodone/Oxymorphone, Urine Screen with Reflex to Quantitation