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Recommendations when to order or not order the test. May include related or preferred tests.
Use to detect and quantitate PML-RARA fusion transcripts in patients with acute promyelocytic leukemia. Use to monitor minimal residual disease and assess the risk of disease relapse.
New York DOH Approval Status
Indicates whether a test has been approved by the New York State Department of Health.
This test is New York state approved.
Specimen Required
Patient PreparationInstructions patient must follow before/during specimen collection.
CollectSpecimen type to collect. May include collection media, tubes, kits, etc.
Whole blood or bone marrow in lavender (EDTA).
Specimen PreparationInstructions for specimen prep before/after collection and prior to transport.
Whole Blood: Transport 5 mL whole blood. (Min: 3 mL) Bone Marrow: Transport 3 mL bone marrow. (Min: 1 mL) Refrigerate immediately. Specimens must be received within 48 hours of collection due to lability of RNA.
Storage/Transport TemperaturePreferred temperatures for storage prior to and during shipping to ARUP. See Stability for additional info.
Whole Blood and Bone Marrow: CRITICAL REFRIGERATED. Separate specimens must be submitted when multiple tests are ordered.
Unacceptable ConditionsCommon conditions under which a specimen will be rejected.
Serum, plasma, extracted DNA, CSF, FFPE tissue, ambient whole blood, or frozen whole blood or bone marrow. Specimens collected in anticoagulants other than EDTA. Severely hemolyzed or clotted specimens. Ambient bone marrow specimens past 7 days will be canceled. Refrigerated whole blood or bone marrow specimens past 7 days will be canceled.
RemarksAdditional specimen collection, transport, or test submission information.
StabilityAcceptable times/temperatures for specimens. Times include storage and transport time to ARUP.
Expected turnaround time for a result, beginning when ARUP has received the specimen.
2-9 days
Reference Interval
Normal range/expected value(s) for a specific disease state. May also include abnormal ranges.
By report
Interpretive Data
May include disease information, patient result explanation, recommendations, or details of testing.
Refer to report.
Compliance Category
Laboratory Developed Test (LDT)
Note
Additional information related to the test.
Hotline History
N/A
CPT Codes
The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Other names that describe the test. Synonyms.
AMPL' APL
APL MRD
APL Post-consolidation therapy testing
PML-RARA fusion types, A, B, B variant
PML-RARA long, short, variable types
PML-RARA S, L, V forms
PML_RARA fusion types
Quantitative PML
t(15;17)
PML-RARA Detection by RT-PCR, Quantitative (Test on Referral as of 1/17/2023)
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