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Hepatitis C Virus Antibody by CIA
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Preferred single screening test for a one time screening of population born between 1945-1965 and individuals at risk for HCV. Positive results require confirmation by molecular testing (eg, Hepatitis C Virus (HCV) by Quantitative NAAT (3000572) or Hepatitis C Virus (HCV) by Quantitative NAAT with Reflex to HCV Genotype by Sequencing (3000576)).
Qualitative Chemiluminescent Immunoassay
Sun-Sat
Within 24 hours
Serum Separator Tube (SST). Also acceptable: Lavender (EDTA) or Pink (K2EDTA).
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Refrigerated.
Specimens containing particulate material. Severely hemolyzed, heat-inactivated, or lipemic specimens. Heparinized plasma.
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: Indefinitely (avoid freeze/thaw cycles)
Negative
This assay should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P).
| Hepatitis C Antibody by CIA Index | |
|---|---|
| Negative | 0.79 IV or less |
| Equivocal | 0.80 to 0.99 IV |
| Low Positive | 1.00 to 10.99 IV |
| High Positive | 11.00 IV or greater |
| Index Value (IV) = Anti-HCV signal to cutoff (S/C) | |
No compliance statements are in use for this test.
For both low-positive and high-positive anti-HCV screening results, ARUP recommends collecting a new specimen and testing for Hepatitis C RNA by PCR to rule out active infection.
86803
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0020099 | Hepatitis C Antibody by CIA Interp | 13955-0 |
| 2002404 | Hepatitis C Antibody by CIA Index | 48159-8 |
- Anti-HCV
- HCV Ab
- HCV Antibody
- HCVAB, Serum
- Hepatitis C Viral Antibody, Serum
- non-A, non-B Hepatitis
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