Aid in the diagnosis and prognostication of Crohn disease.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Serum separator tube (SST).
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Plasma, other body fluids, grossly icteric, heat-inactivated, grossly hemolyzed, severely lipemic, or contaminated specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
(avoid repeated freeze/thaw cycles)
|Saccharomyces cerevisiae Ab (gASCA), IgG||
|Laminaribioside Carbohydrate Ab ALCA IgG||
|Mannobioside Carbohydrate Ab (AMCA), IgG||
|Chitobioside Carbohydrate Ab (ACCA), IgA||
Anti-glycan serologic markers may serve as an aid in the diagnosis of Crohn disease (CD) and an indicator of disease prognosis. Anti-saccharomyces cerevisiae antibody (gASCA) has the highest diagnostic value and anti-chitobioside carbohydrate antibody (ACCA) has the highest association with more-aggressive disease. Both ACCA and gASCA are associated equally with the need for surgery. When found in combination, these markers have the best diagnostic potential. A combination of two or more of the four anti-glycan markers have a significant association with complications and the need for surgery than any single marker alone. A negative result does not rule out CD.
Analyte Specific Reagent (ASR)
86671; 83516 x3
|Component Test Code*||Component Chart Name||LOINC|
|2001609||Saccharomyces cerevisiae Ab (gASCA), IgG||47321-5|
|2001610||Mannobioside Carbohydrate Ab (AMCA), IgG||53597-1|
|2001611||Laminaribioside Carbohydrate Ab ALCA IgG||53596-3|
|2001612||Chitobioside Carbohydrate Ab (ACCA), IgA||53594-8|
|2013334||Crohn Disease Prognostic Pan Interp.||62364-5|
- Chitobioside Carbohydrate Antibody (ACCA), IgA
- Glycan Antibodies
- IBD Prognostic Panel
- Inflammatory Bowel Disease Prognostic Panel
- Laminaribioside Carbohydrate Antibody (ALCA), IgG
- Saccharomyces cerevisiae Antibody (gASCA), IgG