Ordering Recommendation

Not recommended as a stand-alone test. Refer to Arbovirus Antibodies, IgG and IgM, CSF (2001597).

New York DOH Approval Status

Testing is not New York state approved. Specimens from New York clients will be sent out to a New York state-approved laboratory.

Specimen Required

Patient Preparation


Specimen Preparation

Transfer 4 mL CSF to an ARUP Standard Transport Tube. (Min: 1.5 mL)
New York State Clients: 1 mL CSF (Min: 0.1 mL) AND CSF 2 mL (Min: 0.7 mL)

Storage/Transport Temperature

New York State Clients: Frozen

Unacceptable Conditions

Plasma. Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.


Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
New York State Clients: Ambient: 4 days; Refrigerated: 1 week; Frozen: 1 month


Semi-Quantitative Indirect Fluorescent Antibody/Semi-Quantitative Enzyme-Linked Immunosorbent Assay


Tue, Fri


1-5 days

Reference Interval

Test Number
Reference Interval
  West Nile Virus Antibody IgG CSF 1.29 IV or less
  California Encephalitis IgG CSF Less than 1:1
  St. Louis Encephalitis Ab, IgG, CSF Less than 1:1
  Eastern Equine Enceph Ab, IgG, CSF Less than 1:1
  Western Equine Enceph Ab, IgG, CSF Less than 1:1

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Component Interpretation
West Nile Virus Antibody, IgG by ELISA, CSF 1.29 IV or less: Negative - No significant level of West Nile virus IgG antibody detected.
1.30-1.49 IV: Equivocal - Questionable presence of West Nile virus IgG antibody detected.  Repeat testing in 10-14 days may be helpful.
1.50 IV or greater: Positive - Presence of IgG antibody to West Nile virus detected, suggestive of current or past infection.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes

86651; 86652; 86653; 86654; 86789


Component Test Code* Component Chart Name LOINC
0050238 West Nile Virus Antibody IgG CSF 39572-3
0098893 California Encephalitis IgG CSF 49138-1
0098895 St. Louis Encephalitis Ab, IgG, CSF 21509-5
0098896 Eastern Equine Enceph Ab, IgG, CSF 10897-7
0098897 Western Equine Enceph Ab, IgG, CSF 9315-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


Arbovirus Antibodies, IgG, CSF