Useful as a biomarker of acute thallium exposure. For the assessment of chronic exposure, consider Thallium, Urine (0025019).
Quantitative Inductively Coupled Plasma-Mass Spectrometry
Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician).
Royal Blue (K2EDTA or Na2EDTA).
Transport 7 mL whole blood in the original collection tube. (Min: 0.5 mL)
Room temperature. Also acceptable: Refrigerated.
Specimens collected in tubes other than Royal Blue (EDTA). Specimens transported in containers other than a Royal Blue (EDTA) tube or Trace Element-Free Transport Tube. Heparin anticoagulant. Clotted specimens.
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Less than or equal to 2.0 µg/L
Elevated results may be due to skin or collection-related contamination, including the use of a noncertified metal-free collection/transport tube. If contamination concerns exist due to elevated levels of blood thallium, confirmation with a second specimen collected in a certified metal-free tube is recommended.
Blood thallium levels reflect recent exposure as thallium has a biological half-life of approximately 2 to 4 days. Blood levels greater than 100 µg/L are considered toxic and greater than 300 µg/L indicate severe ingestion. After severe thallium poisonings, reported symptoms have varying times of onset and include gastroenteritis, multi-organ failure and neurologic injury. Peripheral neuropathy and alopecia are well-documented effects of acute and chronic exposure. Human health effects from low-level thallium exposure are unknown.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
- WB thallium