Ordering Recommendation
Panel that combines varicella-zoster virus IgG and IgM antibodies is preferred (0050162).
Mnemonic
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Mon-Fri
Reported
1-5 days
New York DOH Approval Status
Specimen Required
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."
Refrigerated.
Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
0.90 ISR or less: Negative - No significant level of detectable varicella-zoster virus IgM antibody.
0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 ISR or greater: Positive - Significant level of detectable varicella-zoster virus IgM antibody. Indicative of current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization.
Interpretive Data
FDA
Note
Hotline History
CPT Codes
86787
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0099314 | Varicella-Zoster Virus Antibody, IgM | 5404-9 |
Aliases
- Herpes Zoster
- Herpes Zoster IgM antibodies
- Varicella Zoster Virus IgM
- Varicella-Zoster Virus Antibody, IgM, Serum
- VZV Antibody, IgM
- VZV IgM