Ordering Recommendation
May aid in diagnosing acute infections and detecting past exposure and/or vaccination.
Mnemonic
VZV PAN
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Serum separator tube.
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
See individual components.
Remarks
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
Test Number |
Components |
Reference Interval |
---|---|---|
Varicella-Zoster Virus Antibody, IgM | 0.90 ISR or less |
Interpretive Data
Component Result |
Interpretation |
---|---|
Varicella-Zoster Virus Antibody, IgG | 134.9 IV or less: Negative - No significant level of detectable varicella-zoster IgG antibody. 135.0-164.9 IV: Equivocal - Repeat testing in 10-14 days may be helpful. 165.0 IV or greater: Positive - IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection. |
Varicella-Zoster Virus Antibody, IgM | 0.90 ISR or less: Negative - No significant level of detectable varicella-zoster virus IgM antibody. 0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful. 1.10 ISR or greater: Positive - Significant level of detectable varicella-zoster virus IgM antibody. Indicative of current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization. |
Compliance Category
FDA
Note
Hotline History
N/A
CPT Codes
86787 x2
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050167 | Varicella-Zoster Virus Ab, IgG | 5403-1 |
0099314 | Varicella-Zoster Virus Antibody, IgM | 5404-9 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- Herpes Zoster
- Varicella Zoster Virus
- VZV
- VZV Antibodies, IgG & IgM
- VZV antibody panel
- VZV panel
Varicella-Zoster Virus Antibodies, IgG and IgM