Sertraline

0098745
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Example Reports
High
Normal
Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic
SERTRALINE
Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Wed

Reported

1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Remarks
Stability

After separation from cells: Ambient: 5 days; Refrigerated: 2 weeks; Frozen: 6 months

Reference Interval

Effective November 18, 2013

Therapeutic Range: Not well established.
Toxic: Greater than 300 ng/mL

Interpretive Data

Sertraline doses ranging from 50-200 mg/d produce serum concentration ranging from 30-200 ng/mL. Dosing above 200 mg/d is associated with increased adverse effects and decreased efficacy. Adverse effects may include dry mouth, headache, dizziness, somnolence, nausea and diarrhea.

Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
02/19/2019
X
X
N/A
CPT Codes

80332 (Alt code: G0480)

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Components
Component Test Code* Component Chart Name LOINC
0098745 Sertraline 6906-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Desmethylsertraline
  • Lustral
  • sertraline blood level
  • Zoloft
  • zoloft blood level
Sertraline