Ordering Recommendation

Rarely indicated. If serum estrone measurement is needed, preferred test is Estrogens, Fractionated by Tandem Mass Spectrometry (0093248).

Mnemonic
ESTRNE TMS
Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry

Performed

Sun-Sat

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 1 week; Frozen: 1 month

Reference Interval
Reference Intervals for Estrone-Children
Tanner Stages:
I
II
III
IV and V
Males
less than 7.0 pg/mL
less than 11.0 pg/mL
1.0-31.0 pg/mL
2.0-30.0 pg/mL
Females
less than 27.0 pg/mL
1.0-39.0 pg/mL
8.0-117.0 pg/mL
4.0-109.0 pg/mL
Age Group
7-9
10-12
13-15
16-17
Males
less than 7.0 pg/mL
less than 11.0 pg/mL
1.0-30.0 pg/mL
1.0-32.0 pg/mL
Females
less than 20.0 pg/mL
1.0-40.0 pg/mL
8.0-105.0 pg/mL
4.0-133.0 pg/mL

Reference Intervals for Estrone-Adults
Females 18 Years and Older
Males 18 Years and Older
Premenopausal:
Early Follicular: less than 150.0 pg/mL
Late Follicular: 100.0-250.0 pg/mL
Luteal: less than 200.0 pg/mL
9.0-36.0 pg/mL
Postmenopausal: 3.0-32.0 pg/mL

Interpretive Data



Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

82679

Components
Component Test Code* Component Chart Name LOINC
0093249 Estrone by TMS 2258-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Estrone (E1)
Estrone, by Tandem Mass Spectrometry