Methadone and Metabolite, Urine, Quantitative

0090362
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Example Reports
Negative
Positive

Ordering Recommendation

Preferred test to follow-up presumptive results. For general screening, Methadone Urine Screen with Reflex to Quantitation (2012245) is preferred.

Mnemonic

CDCO METH

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Sun-Sat

Reported

1-4 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Random urine.

Specimen Preparation

Transfer 1 mL with no additives or preservatives urine to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Room temperature.

Unacceptable Conditions

Specimens exposed to repeated freeze/thaw cycles.

Remarks
Stability

Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 years

Reference Interval

Drugs Covered Cutoff Concentrations
Methadone 100 ng/mL
EDDP 100 ng/mL

Interpretive Data

Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Positive cutoff: 100 ng/mL

For medical purposes only; not valid for forensic use.

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Compare to Pain Management, Methadone, Quantitative, with medMATCH, Urine; Pain Management, Methadone, with Confirmation with medMATCH, Urine.

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
10/03/2022
X
X
N/A

CPT Codes

80358 (Alt code: G0480)

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Components

Component Test Code* Component Chart Name LOINC
2005890 Methadone, Urn, Quant 3774-7
2005891 EDDP, Urn, Quant 50542-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Amidone
  • Dolophine
  • EDDP
  • Heptadon
  • Methadone
  • Methadose
  • Pain Management
  • Physeptone
  • Symoron
Methadone and Metabolite, Urine, Quantitative