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Librium and Nordiazepam
Ordering Recommendation
Use to optimize dosing and monitor patient adherence.
New York DOH Approval Status
Specimen Required
Timing of specimen collection: Predose (trough) draw at steady state concentration.
Gray (potassium oxalate/sodium fluoride). Also acceptable: Plain red, green (sodium heparin), lavender (K2 or K3EDTA) or pink (K2EDTA).
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP standard transport tube. (Min: 1 mL)
Refrigerated.
Gel separator tubes. Plasma or whole blood collected in light blue (sodium citrate). Hemolyzed specimens.
After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years (Avoid repeated freeze/thaw cycles)
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Tue, Fri
Reported
1-7 days
Reference Interval
Effective November 16, 2015
| Components |
Therapeutic Range |
|---|---|
| Librium | 500-3000 ng/mL - Dose (Adult): 5-100 mg Toxic: Greater than 5000 ng/mL |
| Nordiazepam | 100-1500 ng/mL - Based on normal dosages. Toxic: Greater than 2500 ng/mL |
Interpretive Data
Adverse effects may include drowsiness, ataxia, nausea, and constipation.
Standard
Note
Hotline History
Hotline History
CPT Codes
80346 (Alt code: G0480)
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0090150 | Librium | 3457-9 |
| 0090195 | Nordiazepam | 3537-8 |
Aliases
- Chlordiazepoxide
- Chlordiazepoxide and Metabolite
- Kolpoxide
- Librax
- Libritabs
- Librium and Metabolite
- librium and nordiazepam blood level
- Misural
- Mitran
- Multom
- Poxi
- Risolid
- Sonimen
- Tropium
- Vovapam
- Zetran
