Mucopolysaccharides Screen - Electrophoresis and Quantitation, Urine

0081352
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Example Reports
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Mucopolysaccharides (MPS) Testing Patient History Form

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Additional Technical Information

Ordering Recommendation

Use to evaluate symptomatic patients for mucopolysaccharidoses (MPS). To monitor glycosaminoglycans (GAGs) in patients previously diagnosed with MPS, refer to Mucopolysaccharides, Quantitative, Urine (0081357).

Mnemonic

MPS SCREEN

Methodology

Electrophoresis/Spectrophotometry

Performed

Tue

Reported

4-14 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Morning void preferred.

Collect

Urine.

Specimen Preparation

Freeze specimen immediately. Transport 20 mL urine. (Min: 10 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Specimens containing preservatives.

Remarks
Stability

Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month (avoid repeated freeze/thaw cycles)

Reference Interval

Test Number
 Components
 Reference Interval
  Mucopolysaccharides mg/mmol CRT
Age
 Reference Interval (mg/mmol creatinine)
0-5 months 14.6-47.8
6-11 months 3.7-35.5
1-2 years 5.4-30.8
3-6 years 5.2-16.7
7-13 years 2.4-10.2
14 years or older 0.0-7.1

Interpretive Data

Mucopolysaccharides (Glycosaminoglycans) include:  Keratan Sulfate, Heparan Sulfate, Dermatan Sulfate, and Chondroitin Sulfates 4 and 6.  The excretion of Heparan Sulfate is variable.  A normal mucopolysaccharides screen does not exclude Sanfilippo Syndrome (Mucopolysaccharidosis Type III).

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

82664; 83864

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Components

Component Test Code* Component Chart Name LOINC
0081353 MPS Electrophoresis
0081355 Mucopolysaccharides mg/mmol CRT 46132-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Chondroitin Sulfate
  • Dermatan Sulfate
  • GAG(s)
  • Glycosaminoglycans
  • Heparan Sulfate
  • Urine mucopolysaccharides
  • urine mucopolysaccharides screen
Mucopolysaccharides Screen - Electrophoresis and Quantitation, Urine