Ordering RecommendationRecommendations when to order or not order the test. May include related or preferred tests.
Use for assessment of multiple sclerosis. Detect unique IgG oligoclonal bands in cerebrospinal fluid (CSF) in conjunction with a matched serum specimen. Preferred test is Oligoclonal Band Profile (0080440).
MnemonicUnique test identifier.
OLIGOB
MethodologyProcess(es) used to perform the test.
Qualitative Isoelectric Focusing/Electrophoresis
PerformedDays of the week the test is performed.
Sun-Sat
ReportedExpected turnaround time for a result, beginning when ARUP has received the specimen.
1-3 days
New York DOH Approval StatusIndicates test has been approved by the New York State Department of Health.
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
CSF AND serum separator tube or plain red. Serum specimen should be drawn within 48 hours of CSF collection.
Specimen Preparation
Allow serum to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transport 1.5 mL CSF (Min: 0.7 mL) AND transfer 1 mL serum to an ARUP Standard Transport Tube (Min: 0.5 mL).
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Remarks
Stability
Ambient: 8 hours; Refrigerated: 1 week; Frozen: 1 year
Reference IntervalNormal range/expected value(s) for a specific disease state. May also include abnormal ranges.
Effective August 6, 2012
Test Number
Components
Reference Interval
0081139
Oligoclonal Bands, CSF
Negative
2005461
Oligoclonal Bands Number, CSF
0 - 1 Bands
Interpretation
By report
Interpretive DataBackground information for test. May include disease information, patient result explanation, recommendations, details of testing, associated diseases, explanation of possible patient results.
Compliance Category
FDA
NoteAdditional information related to the test.
Specimens must be assayed together for interpretation. This test reports only the number of oligoclonal bands. A patient is considered positive for CSF oligoclonal bands if there are two or more bands in the CSF immunoglobulin region that are not present in the serum. In order to confirm local production of oligoclonal IgG in CSF, a matched serum sample is required. Oligoclonal bands present in CSF, but not in serum, indicate central nervous system production. Oligoclonal bands are performed using isoelectric focusing and immunofixation.
Hotline History
N/A
CPT CodesThe American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
AliasesOther names that describe the test. Synonyms.
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