Ordering Recommendation

Useful as a tumor marker for squamous cell carcinomas of the head and neck, uterine cervix, lung, vulva, and esophagus.


Quantitative Enzyme-Linked Immunosorbent Assay




1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Serum separator tube or plain red.

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature


Unacceptable Conditions

Specimens exposed to repeated freeze/thaw cycles.


After separation from cells: Ambient: 48 hours; Refrigerated: 4 months; Frozen: 4 months

Reference Interval

2.2 ng/mL or less

Interpretive Data

SCC antigen levels alone should not be interpreted as evidence to the presence or absence of malignant disease.  In patients with known or expected cancer, other tests and procedures must be considered for diagnosis and patient management.  Results obtained with different assay methods or kits cannot be used interchangeably.

Compliance Statement A: For laboratory developed tests using a manufacturer labeled ASR as the reagent providing the specificity of the assay. Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.

Hotline History
CPT Codes


Component Test Code* Component Chart Name LOINC
0081054 Squamous Cell Carcinoma Antigen 9679-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • SCC
  • SCC Antigen
  • SCCA
Squamous Cell Carcinoma Antigen, Serum