Ordering Recommendation

Useful as a tumor marker for squamous cell carcinomas of the head and neck, uterine cervix, lung, vulva, and esophagus.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Serum separator tube or plain red.

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature


Unacceptable Conditions

Specimens exposed to repeated freeze/thaw cycles.


After separation from cells: Ambient: 48 hours; Refrigerated: 14 days; Frozen: 2 months






1-8 days

Reference Interval

0.0-1.7 ng/mL

Interpretive Data

This test is performed using the BRAHMS SCC Kryptor kit. Results obtained with different assay methods or kits cannot be used interchangeably. SCC Antigen levels alone should not be interpreted as evidence of the presence or absence of malignant disease. In patients with known or expected cancer, other tests and procedures must be considered for diagnosis and patient management. Elevated concentrations may also occur in benign conditions such as gynecological diseases, inflammatory lung disease, and liver or renal insufficiency.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
3003505 Squamous Cell Carcinoma, Serum 9679-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • SCC
  • SCC Antigen
  • SCCA
Squamous Cell Carcinoma, Serum