Proinsulin, Intact

0070112
copy
 

Copy Utility


emailprint
Example Reports
Abnormal
Normal

Ordering Recommendation

Aids in the detection of insulinoma. Do not use to diagnose diabetes mellitus.

Mnemonic

PROINS

Methodology

Quantitative Chemiluminescent Immunoassay

Performed

Tue, Thu

Reported

1-6 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Patient must fast for 12-15 hours prior to collection.

Collect

Serum Separator Tube (SST) or Plain Red. Also acceptable: Lavender (K2EDTA) or Pink (K2EDTA).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.2 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Grossly hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: Unacceptable; Refrigerated: 48 hours; Frozen: 2 months

Reference Interval

Effective May 19, 2014

Age Reference Interval
0-17 years Not established
18 years and older Less than or equal to 8.0 pmol/L

Interpretive Data

Fasting intact proinsulin values above the reference interval indicate a possible insulin secreting pancreatic tumor (insulinoma) in patients with hypoglycemia. Fasting intact proinsulin values range from 3 to 50 pmol/L in patients with untreated type 2 diabetes.

Compliance Category

FDA

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
05/18/2020
X
N/A

CPT Codes

84206

Are you an ARUP Client? Click here for your pricing.

Components

Component Test Code* Component Chart Name LOINC
0070112 Proinsulin, Intact 10451-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Proinsulin, Plasma
Proinsulin, Intact