New York DOH Approval Status
Collect midmorning after patient has been sitting, standing, or walking for at least 2 hours and seated for 5-15 minutes. Refer to the Additional Technical Information for specific patient preparation recommendations.
Lavender (EDTA) or Pink (K2EDTA). Do not collect in refrigerated tubes.
Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 1.2 mL)
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Serum. Specimens collected in citrate, heparin, or oxalate. Hemolyzed specimens.
Ambient: 6 hours; Refrigerated: Unacceptable; Frozen: 1 month
Quantitative Enzyme-Linked Immunosorbent Assay
|Adult, normal sodium diet
||Children, normal sodium diet, supine:
||Children, normal sodium diet, upright:
|Supine: 0.2-1.6 ng/mL/hr||Newborn (1-7 days): 2.0-35.0 ng/mL/hr||0-3 years: Not Available|
|Upright: 0.5-4.0 ng/mL/hr||Cord blood: 4.0-32.0 ng/mL/hr||4-5 years: Less than or equal to 15 ng/mL/hr|
|1-12 months: 2.4-37.0 ng/mL/hr||6-10 years: Less than or equal to 17 ng/mL/hr|
|13 months-3 years:1.7-11.2 ng/mL/hr||11-15 years: Less than or equal to 16 ng/mL/hr|
|4-5 years:1.0-6.5 ng/mL/hr|
|6-10 years: 0.5-5.9 ng/mL/hr|
|11-15 years: 0.5-3.3 ng/mL/hr|
Plasma renin activity measures enzyme ability to convert angiotensinogen to angiotensin I and is limited by the availability of angiotensinogen. Plasma renin activity is not an accurate indicator of enzyme activity when angiotensinogen is decreased.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Refer to the Additional Technical Information for Endocrine Society recommendations for patient preparation, specimen collection, medications for hypertension control during confirmatory testing for primary aldosteronism, and factors that may lead to false-positive or false-negative aldosterone-renin ratio (ARR) results.
|Component Test Code*||Component Chart Name||LOINC|
- Plasma Renin Activity
- Renin Activity, Plasma