Screen and diagnose hyperaldosteronism.
Quantitative Chemiluminescent Immunoassay/Quantitative Enzyme-Linked Immunosorbent Assay
Collect midmorning after patient has been sitting, standing, or walking for at least 2 hours, and seated for 5-15 minutes. Refer to the Additional Technical Information for specific patient preparation recommendations.
Serum Separator Tube (SST) AND Lavender (K2EDTA) or Pink (K2EDTA). Do not collect in refrigerated tubes.
Separate from cells ASAP or within 2 hours of collection.
Serum: Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Plasma: Transfer 2 mL EDTA plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 1.2 mL)
Both specimens should be collected and submitted together for testing.
Plasma: CRITICAL FROZEN. Separate specimens must be submitted when additional tests are ordered.
Plasma collected in citrate, heparin, or oxalate. Hemolyzed specimens.
Serum: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 1 month
Plasma: Ambient: 6 hours; Refrigerated: Unacceptable; Frozen: 1 month
|0070015||Aldosterone, Serum||Effective May 16, 2011
|Aldosterone/Renin Activity Calculation||Effective May 16, 2011
Less than or equal to 25
An Aldosterone/Renin Activity Ratio of greater than 25 is suggestive of hyperaldosteronism if the aldosterone concentration is greater than 15 ng/dL.
Compliance Statement D: For laboratory tests using a manufactured RUO kit. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Refer to the Additional Technical Information for Endocrine Society recommendations for patient preparation, specimen collection, medications for hypertension control during confirmatory testing for primary aldosteronism, and factors that may lead to false-positive or false-negative ARR results.
|Component Test Code*||Component Chart Name||LOINC|
|0070074||Aldosterone/Renin Activity Calculation||30894-0|
- Aldosterone and Plasma Renin Activity
- Aldosterone serum
- Aldosterone/Renin Activity
- Renin Activity