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Recommendations when to order or not order the test. May include related or preferred tests.
Screen and diagnose hyperaldosteronism.
New York DOH Approval Status
Indicates whether a test has been approved by the New York State Department of Health.
This test is New York state approved.
Specimen Required
Patient PreparationInstructions patient must follow before/during specimen collection.
Collect midmorning after patient has been sitting, standing, or walking for at least 2 hours, and seated for 5-15 minutes. Refer to the Additional Technical Information for specific patient preparation recommendations.
CollectSpecimen type to collect. May include collection media, tubes, kits, etc.
Serum Separator Tube (SST) AND Lavender (K2EDTA) or Pink (K2EDTA). Do not collect in refrigerated tubes.
Specimen PreparationInstructions for specimen prep before/after collection and prior to transport.
Separate from cells ASAP or within 2 hours of collection. Serum: Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) AND Plasma: Transfer 2 mL EDTA plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 1.2 mL)
Storage/Transport TemperaturePreferred temperatures for storage prior to and during shipping to ARUP. See Stability for additional info.
Both specimens should be collected and submitted together for testing. Serum: Frozen. Plasma: CRITICAL FROZEN. Separate specimens must be submitted when additional tests are ordered.
Unacceptable ConditionsCommon conditions under which a specimen will be rejected.
Plasma collected in citrate, heparin, or oxalate. Hemolyzed specimens.
RemarksAdditional specimen collection, transport, or test submission information.
StabilityAcceptable times/temperatures for specimens. Times include storage and transport time to ARUP.
Expected turnaround time for a result, beginning when ARUP has received the specimen.
1-5 days
Reference Interval
Normal range/expected value(s) for a specific disease state. May also include abnormal ranges.
Test Number
Components
Reference Interval
Aldosterone
Age
Posture Unspecified (ng/dL)
Supine (ng/dL)
Upright (ng/dL)
0-6 days
5.0-102.0
1-3 weeks
6.0-179.0
1-11 months
7.0-99.0
1-2 years
7.0-93.0
3-10 years
4.0-44.0
11-14 years
4.0-31.0
15 years and older
31.0 or less
16.0 or less
4.0-31.0
Aldosterone/Renin Activity Calculation
Less than or equal to 25
Renin Activity
Age
Supine (ng/mL/hr) Normal sodium diet
Upright (ng/mL/hr) Normal sodium diet
Cord blood
4.0-32.0
Not Available
Newborn (1-7 days)
2.0-35.0
Not Available
1-12 months
2.4-37.0
Not Available
13 months-3 years
1.7-11.2
Not Available
4-5 years
1.0-6.5
Less than or equal to 15
6-10 years
0.5-5.9
Less than or equal to 17
11-15 years
0.5-3.3
Less than or equal to 16
Adult
0.2-1.6
0.5-4.0
Interpretive Data
May include disease information, patient result explanation, recommendations, or details of testing.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Compliance Category
Laboratory Developed Test (LDT)
Note
Additional information related to the test.
Refer to the Additional Technical Information for Endocrine Society recommendations for patient preparation, specimen collection, medications for hypertension control during confirmatory testing for primary aldosteronism, and factors that may lead to false-positive or false-negative ARR results.
Hotline History
N/A
CPT Codes
The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.