Ordering Recommendation

The combined aldosterone/renin tests are preferred when screening for hyperaldosteronism. Refer to Aldosterone/Renin Activity Ratio (0070073) or Aldosterone and Renin, Direct with Ratio (2002582).

Mnemonic
ALDOST
Methodology

Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Collect midmorning after patient has been sitting, standing or walking for at least 2 hours and seated for 5-15 minutes. Refer to the Additional Technical Information for specific patient preparation recommendations.

Collect

Serum Separator Tube (SST) or Plain Red.

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

EDTA plasma.

Remarks
Stability

After separation from cells: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 1 month

Reference Interval

Effective May 16, 2011

Age
Posture Unspecified
Supine
Upright
0-6 days 5.0-102.0 ng/dL
1-3 weeks 6.0-179.0 ng/dL
1-11 months 7.0-99.0 ng/dL
1-2 years 7.0-93.0 ng/dL
3-10 years 4.0-44.0 ng/dL
11-14 years 4.0-31.0 ng/dL
15 years and older Less than or equal to 31.0 ng/dL Less than or equal to 16.0 ng/dL 4.0-31.0 ng/dL

Interpretive Data

Normal serum levels of aldosterone are dependent on the sodium intake and whether the patient is upright or supine. High sodium intake will tend to suppress serum aldosterone, whereas low sodium intake will elevate serum aldosterone. The reference intervals for serum aldosterone are based on normal sodium intake.

No compliance statements are in use for this test.

Note

Refer to the Additional Technical Information for Endocrine Society recommendations for patient preparation, specimen collection, medications for hypertension control during confirmatory testing for primary aldosteronism, and factors that may lead to false-positive or false-negative aldosterone-renin ratio (ARR) results.

Hotline History
N/A
CPT Codes

82088

Components
Component Test Code* Component Chart Name LOINC
0070015 Aldosterone 1763-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Aldosterone, S
  • serum aldosterone
Aldosterone, Serum