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Tissue Transglutaminase Antibody, IgG
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• Recommended single screening test for IgA-deficient individuals with suspected celiac disease. (IgA testing recommended to identify IgA deficiency.)
• May aid in monitoring adherence to gluten-free diet in celiac disease confirmed patients.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Sun-Sat
1-2 days
Serum separator tube.
Remove serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Refrigerated.
Plasma. Hemolyzed or severely lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
| 5 U/mL or less | Negative |
| 6-9 U/mL | Weak Positive |
| 10 U/mL or greater | Positive |
The tTG IgG assay may aid in the diagnosis of gluten-sensitivity enteropathy (i.e., celiac disease, dermatitis herpetiformis) in tTG IgA negative patients with confirmed IgA deficiency. A negative tTG IgG test alone does not rule out gluten-sensitive enteropathy.
No compliance statements are in use for this test.
Human recombinant tTG antigen is utilized in this assay
83516
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0056009 | Tissue Transglutaminase Antibody,IgG | 56537-4 |
- Tissue Transglutaminase
- Transglutaminase
- tTG
- tTG IgG
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