• Recommended single screening test for IgA-deficient individuals with suspected celiac disease. (IgA testing recommended to identify IgA deficiency.)
• May aid in monitoring adherence to gluten-free diet in celiac disease confirmed patients.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Serum separator tube.
Remove serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Plasma. Hemolyzed or severely lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
|5 U/mL or less||Negative|
|6-9 U/mL||Weak Positive|
|10 U/mL or greater||Positive|
The tTG IgG assay may aid in the diagnosis of gluten-sensitivity enteropathy (i.e., celiac disease, dermatitis herpetiformis) in tTG IgA negative patients with confirmed IgA deficiency. A negative tTG IgG test alone does not rule out gluten-sensitive enteropathy.
Human recombinant tTG antigen is utilized in this assay
|Component Test Code*||Component Chart Name||LOINC|
|0056009||Tissue Transglutaminase Antibody,IgG||56537-4|
- Tissue Transglutaminase
- tTG IgG