Ordering Recommendation

Acceptable single screening test for celiac disease. IgA testing recommended to identify IgA deficiency. Use IgG test in individuals who are IgA deficient. May be useful in diagnosing children <2 years who test negative for tTG and EMA antibodies. May aid in monitoring adherence to gluten-free diet. Celiac Disease Reflexive Cascade (2008114) or Tissue Transglutaminase (tTG) Antibody, IgG (0056009) is the preferred test for screening patients with suspected celiac disease.

Mnemonic

GLIADPEP G

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transport 0.5 mL serum. (Min: 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma or other body fluids. Contaminated, hemolyzed, grossly icteric, or grossly lipemic specimens.

Remarks
Stability

After separation from cells:  Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval

19 Units or less Negative
20-30 Units Weak Positive
31 Units or greater Positive

Interpretive Data



Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86258

Components

Component Test Code* Component Chart Name LOINC
0051359 Deamidated Gliadin Peptide (DGP) Ab, IgG 63459-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Celiac Disease Antibodies
  • Deamidated Gliadin Antibodies (DGP)
  • Deaminated Gliadin Peptide Antibodies
  • DGP
  • DGP Ab
  • DGP IgG
Deamidated Gliadin Peptide (DGP) Antibody, IgG