Ordering Recommendation
Mnemonic
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Mon-Fri
Reported
1-5 days
New York DOH Approval Status
Specimen Required
CSF.
Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Refrigerated.
Bacterially contaminated, heat-inactivated, hemolyzed, or xanthochromic specimens.
Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval
0.90 ISR or less | Negative - No significant level of IgM antibody to varicella-zoster virus detected. |
0.91-1.09 ISR | Equivocal - Repeat testing in 10-14 days may be helpful. |
1.10 ISR or greater | Positive - Significant level of IgM antibody to varicella-zoster virus detected, which may indicate current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. |
Interpretive Data
The detection of antibodies to varicella-zoster in CSF may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Modified FDA
Note
Hotline History
CPT Codes
86787
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0054445 | VZV Antibody IgM CSF | 31695-0 |
Aliases
- Herpes Zoster
- Varicella Zoster Virus CSF IgM
- VZV CSF IgM