Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG with Reflex to Type 1 and 2 Glycoprotein G-Specific Ab, IgG
Ordering Recommendation
Preferred testing for herpes simplex virus (HSV) when exposure to HSV is suspected.
May be useful in identifying a subclinical HSV infection. If results are positive for HSV type 1/2 combined antibodies but negative for both type-specific antibodies, follow-up testing at least one month later is recommended because glycoprotein antibodies may require 3-6 months to form; refer to Herpes Simplex Type 1 and Type 2 Glycoprotein G-Specific Antibodies, IgG by CIA (0051152).
New York DOH Approval Status
Specimen Required
Serum separator tube.
Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Mark specimens plainly as "acute" or "convalescent."
Refrigerated.
Plasma or urine. Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Methodology
Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
1-2 days
Reference Interval
Interpretive Data
Component | Interpretation |
---|---|
Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG by Chemiluminescent Immunoassay | 0.89 IV or less: Not Detected. 0.90-1.09 IV: Indeterminate - Repeat testing in 10-14 days may be helpful. 1.10 IV or greater: Detected. |
FDA
Note
If HSV 1 and/or 2 IgG is 1.10 IV or greater, then HSV 1 gG-Specific IgG and HSV 2 gG-Specific IgG will be added. Additional charges apply.
Hotline History
CPT Codes
86694; if reflexed, add 86695; 86696
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050286 | HSV Type 1/2 Combined Ab, IgG | 27948-9 |
Aliases
- glycoprotein type-specific reactivity
- Herpes Simplex Antibodies, IgG
- Herpes Simplex Serology, Serum HSV 1,2
- HerpeSelect
- HSV
- HSV 1, 2 IgG
- HSV 1,2
- HSV 1,2 glycoprotein
- HSV glycoprotein G
- HSV glycoprotein G-based type-specific serology