0051152
print

Herpes Simplex Type 1 and Type 2 Glycoprotein G-Specific Antibodies, IgG by CIA

HERP PAN 2
Example Reports
Negative
Positive

Ordering Recommendation

In the absence of active lesions, this is the preferred serology test for diagnosing herpes simplex viral infection.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube or plasma separator tube (PST).
Also acceptable: green (lithium heparin) or lavender (K2EDTA or K3EDTA).

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimen. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, grossly hemolyzed, lipemic, or severely icteric specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 14 Days; Frozen: 12 weeks (May have up to 5 freeze/thaw cycles.)

Methodology

Semi-Quantitative Electrochemiluminescent Immunoassay (ECLIA)

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

Test Number
 Components
 Reference Interval
  HSV 1 Glycoprotein G Ab, IgG Less than or equal 0.99 COI
  HSV 2 Glycoprotein G Antibody, IgG Less than or equal to 0.99 COI

Interpretive Data

Individuals infected with HSV may not exhibit detectable IgG antibody to type-specific HSV antigens 1 and 2 in the early stages of infection. Detection of antibody presence in these cases may only be possible using a nontype specific screening test.


HSV 1 Glycoprotein G Ab, IgG
REFERENCE INTERVAL INTERPRETIVE COMMENT
0.99 COI or less Negative: No significant level of detectable IgG antibody to HSV type 1 glycoprotein G.
1.00 COI or greater Positive: IgG antibody to HSV type 1 glycoprotein G detected, which may indicate a current or past HSV infection

HSV 2 Glycoprotein G Antibody, IgG
REFERENCE INTERVAL INTERPRETIVE COMMENT
0.99 COI or less Negative: No significant level of detectable IgG antibody to HSV type 2 glycoprotein G.
1.00 COI or greater Positive: IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection.

Compliance Category

FDA

Note

For CSF, refer to Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by ELISA, CSF (ARUP test code 0050379) and Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by ELISA, CSF (ARUP test code 0050359).

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
04/20/2026
X
X
X
X
X
N/A

CPT Codes

86695; 86696

Are you an ARUP Client? Click here for your pricing.

Components

Component Test Code* Component Chart Name LOINC
0050292 HSV 1 Glycoprotein G Ab, IgG 42337-6
0050294 HSV 2 Glycoprotein G Antibody, IgG 42338-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • HSV
  • HSV glycoprotein G type 1 and 2
  • HSV typing 1 and 2
Herpes Simplex Type 1 and Type 2 Glycoprotein G-Specific Antibodies, IgG by CIA