TORCH Antibodies, IgM

0050665
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Example Reports
Detected
Not Detected

Ordering Recommendation

Not recommended for diagnosing congenital infections in newborns; tests should be selected individually to target the most likely infectious agents.

Mnemonic

TORCH M

Methodology

Semi-Quantitative Chemiluminescent Immunoassay/Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks

Mark specimens plainly as "acute" or "convalescent."

Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Test Number
 Components
 Reference Interval
  Rubella Antibody IgM 19.9 AU/mL or less
  CMV Antibody IgM 29.9 AU/mL or less
  Toxoplasma gondii Ab, IgM 7.9 AU/mL or less
  HSV 1 and/or 2 Abs, IgM by ELISA 0.89 IV or less

Interpretive Data




Component Interpretation
Cytomegalovirus Antibody, IgM 29.9 AU/mL or less:  Not Detected.
30.0-34.9 AU/mL:  Indeterminate - Repeat testing in 10-14 days may be helpful.
35.0 AU/mL or greater:  Detected - IgM antibody to CMV detected, which may indicate a current or recent infection.  However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgM by ELISA 0.89 IV or less:  Not Detected.
0.90-1.09 IV:  Indeterminate - Repeat testing in 10-14 days may be helpful.
1.10 IV or greater:  Detected - IgM antibody to HSV detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
Rubella Antibody, IgM 19.9 AU/mL or less:  Not Detected.
20.0 - 24.9 AU/mL:  Indeterminate - Repeat testing in 10-14 days may be helpful.
25.0 AU/mL or greater:  Detected - IgM antibody to rubella detected, which may indicate a current or recent infection or immunization.
Toxoplasma gondii Antibody, IgM 7.9 AU/mL or less:  Not Detected.
8.0-9.9 AU/mL:  Indeterminate - Repeat testing in 10-14 days may be helpful.
10.0 AU/mL or greater:  Detected - Significant level of Toxoplasma gondii IgM antibody detected and may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

Compliance Category

FDA

Note

This test should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P).

Hotline History

N/A

CPT Codes

86645; 86694; 86762; 86778

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Components

Component Test Code* Component Chart Name LOINC
0050551 Rubella Antibody IgM 5335-5
0050553 CMV Antibody IgM 7853-5
0050557 Toxoplasma gondii Ab, IgM 8040-8
0050641 HSV 1 and/or 2 Abs, IgM by ELISA 41399-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Cytomegalic Inclusion Disease (CMID)
  • Cytomegalovirus (CMV)
  • Herpes Simplex Virus (HSV)
  • TORCH
  • TORCH IgM
  • TORCH Profile IgM
  • Toxoplasma gondii (T. gondii)
  • Toxoplasmosis
TORCH Antibodies, IgM