Ordering Recommendation
Evaluate protein composition of cerebrospinal fluid (CSF); not useful for the assessment of multiple sclerosis for which Oligoclonal Bands in CSF and Serum (0081135) should be ordered.
Mnemonic
Methodology
Quantitative Electrophoresis
Performed
Mon, Wed, Fri
Reported
1-5 days
New York DOH Approval Status
Specimen Required
CSF.
Transport 1 mL CSF. (Min: 0.5 mL)
Refrigerated.
Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 month
Reference Interval
Total Protein: 15-45 mg/dL Alpha-2: 0.0-5.4 mg/dL
Pre-albumin: 0.0-3.1 mg/dL Beta: 0.0-8.1 mg/dL
Albumin: 8.4-34.2 mg/dL Gamma: 0.0-5.4 mg/dL
Alpha-1: 0.0-3.1 mg/dL
Interpretive Data
FDA
Note
CSF electrophoresis may be useful in the diagnosis of tumors in the central nervous system or neurological illness. Oligoclonal Band Profile (ARUP test code 0080440) may be more appropriate for patients with suspected multiple sclerosis. Myelin Basic Protein (ARUP test code 0080515) offers little incremental value in the evaluation of multiple sclerosis. For the evaluation of blood brain barrier integrity, Immunoglobulin G, CSF Index (ARUP test code 0050676), included in the Oligoclonal Band Profile test, may be useful.
Hotline History
CPT Codes
84157; 84166
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050015 | Albumin, CSF | 2861-3 |
0050040 | Alpha-1, CSF | 2864-7 |
0050045 | Alpha-2, CSF | 2867-0 |
0050115 | Beta, CSF | 2870-4 |
0050275 | Gamma, CSF | 2873-8 |
0050430 | Pre-Albumin, CSF | 2876-1 |
0050560 | Total Protein, CSF | 2880-3 |
Aliases
- Electrophoresis, Protein, Spinal Fluid