Ordering Recommendation
May aid in the diagnosis of Crohn disease. Test by itself is not diagnostic and should be used in conjunction with other parameters to confirm disease. Inflammatory Bowel Disease Differentiation Panel (3003748) is the preferred test.
Mnemonic
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
Specimen Required
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Refrigerated.
Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
Test Number |
Components |
Reference Interval |
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---|---|---|---|---|---|---|---|---|
S. cerevisiae Antibody, IgG |
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S. cerevisiae Antibody, IgA |
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Interpretive Data
Saccharomyces cerevisiae IgG antibodies are found in 60-70% of Crohn disease (CD) patients and 10-15% of ulcerative colitis (UC) patients. Saccharomyces cerevisiae IgA antibodies are found in about 35% of CD patients but less than 1% in UC patients. Detection of both Saccharomyces IgG and IgA antibodies in the same serum specimen is highly specific for CD.
FDA
Note
This test may be a useful tool for distinguishing ulcerative colitis (UC) from Crohn disease (CD) in patients with suspected inflammatory bowel disease.
Hotline History
CPT Codes
86671 x2
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050562 | S. cerevisiae Antibody, IgG | 47321-5 |
0050563 | S. cerevisiae Antibody, IgA | 47320-7 |
Aliases
- ASCA
- ASCA Abs
- ASCA IgA
- ASCA IgG
- S. cerevisiae